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Spironolactone migraine with aura12/31/2023 However, these side effects usually improve as you continue taking the medication. In some Western countries, around half of women in their 20s and 30s use it (Germany 52.6%, France 43.8%).Īlthough it has been prescribed for over 50 years and recognized as a safe medication, there may be symptoms such as nausea, headaches, breast tenderness, and swelling when starting to take it because of changes in hormonal balance. The pill is one of the safe drugs used by more than 100 million women worldwide every day. ![]() Who are contraindicated for taking oral contraceptives Our clinic gradually reduces the dosage of spironolactone once the effect of the pill has started to take effect to prevent rebound effects. On the other hand, spironolactone has only temporary effects while it is taken, and rebound effects are known to occur. Combining spironolactone with oral contraceptives can increase the cure rate for acne. Pills containing progesterone that suppresses male hormone activity are prescribed for acne treatment.Īnother medication, spironolactone, has anti-androgenic effects and suppresses male hormone production. The type of progesterone in the pill is also important. Female hormones have effects on the skin such as making the skin texture smoother, reducing pore size, and increasing skin hydration. Oral contraceptives contain small amounts of female hormones and progesterone. Male hormones have undesirable effects on women, such as thickening hair, enlarging sebaceous glands, and worsening acne.Įxcessive male hormone levels or high sensitivity to male hormones can lead to acne in women. ![]() There are two organs that secrete male hormones: the ovaries and the adrenal glands. Mechanism of action for acneĮven women produce “male hormones” in their bodies. It is also recommended for those who suffer from gynecological diseases or symptoms such as irregular periods, menstrual difficulties, polycystic ovary syndrome, endometriosis, and menstrual pain, as it has the ability to improve these conditions. Therefore, it is recommended for those who prefer medications with fewer side effects. If side effects are checked properly, this medication is safe even with long-term use. Hormonal therapy often requires continued treatment even after the skin becomes clear, and the treatment period is usually several years. Another disadvantage is that acne is likely to recur after discontinuing the medication.Įven if it becomes a symptomatic treatment for a limited period of time, it is possible to significantly suppress future acne scarring by completely eliminating all acne once and then continuing with maintenance. On average, acne gradually improves from the fourth month. Additionally, it is known to have a high safety profile, with a low likelihood of causing severe side effects.Īs for its drawbacks, it may take some time for the effects to appear, and a transient worsening of acne is seen in 30% of patients during the first three months of treatment. Hormonal treatment for acne has an effectiveness rate of over 95%, making it a highly effective treatment after isotretinoin. Its anti-androgenic effect, which suppresses male hormones, is used to treat acne. Spironolactone is an old drug that has been used as a diuretic and a treatment for heart failure. In Europe, including France, the Netherlands, and Germany, approximately 50% of women of reproductive age (15-49) take oral contraceptives for birth control purposes, and they are also used as a treatment for acne. ![]() ![]() Low-dose oral contraceptives were developed in the United States in 1973 and are now taken daily by over 100 million women worldwide. We provide hormone therapy for acne using two medications: low-dose oral contraceptives and spironolactone.
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